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Efficacy and safety of taspoglutide monotherapy in drug-naive type 2 diabetic patients after 24 weeks of treatment: results of a randomized, double-blind, placebo-controlled phase 3 study (T-emerge 1)

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GLP-1R is present in the human choroid plexus, where GLP-1R analogs reduces cerebrospinal fluid secretion and intracranial pressure by increasing the intracellular concentration of cyclic adenosine monophosphate and inhibiting the Na + /K + ATPase pump in the choroid plexus [25]